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Neurodevelopmental Toxicity

Developmental Toxicity

Our team of experts can create specialized microBrain platforms to understand the impact of your compound throughout neural development - from neural progenitor cells (NPCs) through mature neural cultures. 

Need to move from in vitro to in vivo neurodevelopmental toxicity studies?  Inquire here for early and IND-enabling pre-clinical studies.

Neurodev tox heatmap.jpg
Neurodev tox heatmap.jpg

Heat maps of neural cultures showing reduced compound susceptibility as culture mature

Nestin.sox1.dapi.merge copy.tif

StemoniX NPCs showing markers of immaturity.

   Nestin

   SOX-1

   DAPI

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