Recent Webinars
StemoniX / Molecular Devices Webinar
Due to the structural and functional complexity of the Central Nervous System (CNS), the ability to obtain accurate and predictive in-vitro models for drug discovery and toxicology screening has been lacking. To fill this gap, StemoniX has developed the microBrain 3D platform: pre-plated neural spheroids composed of human iPSC-derived cortical neurons and astrocytes of uniform composition and size.
This presentation will detail how the Molecular Devices FLIPR Penta and ImageXpress Micro Confocal systems have been used to functionally and structurally characterize microBrain 3D spheroids from both healthy and disease sources.
Key highlights:
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Use of microBrain neuronal microspheroids
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Calcium oscillations in neural spheroids
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3D image analysis of compound treated neural spheroids
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Multi-parametric evaluation of neurotoxicity effects
Virtual Poster Session
ISSCR 2020
The StemoniX microBrain 3D platform was featured in a poster by our partners at
Molecular Devices:
Multiplexed automated assays for neurotoxicity evaluations using induced pluripotent stem cell-derived neural 3D cell models
SoT2020
Simultaneous Assessment of Oncology Compound Efficacy and Toxicity in a Neuronal Human Induced Pluripotent Stem Cell and Glioblastoma-Based High-Throughput Screening Platform
SoT2020
High-Throughput Anisotropic Human iPSC-Derived Cardiomyocyte Cultures Display Differential Response to Chronic Oncology Compound-Related Toxicity
SLAS2020
A Novel Objective Waveform Analysis for Providing Bias-free Multiparametric Outputs for Classifying Biological Mechanisms and High-Throughput Screening Results
SLAS2020
Assessment of compound efficacy and safety for glioblastoma treatment in a multiplexed human High Throughput Screening platform
SLAS2020
A human pancreatic spheroid platform for high throughput screening in toxicology and diabetes
SLAS2020
High Throughput profiling of cardio-active compound response between 2D monolayers, anisotropic and 3-dimensional human induced pluripotent stem cell-derived cardiomyocytes